Access to Cleveland from I-80 (Ohio Turnpike)
  From west to east, the following Interstates provide the easiest (and fastest) access to the City of Cleveland:

• from exit 142, take I-90 eastbound
• from exit 151, take I-480 eastbound
• from exit 161, take I-71 eastbound
• from exit 173, take OH-21 northbound to
  Miller Rd, turn left, drive some 300 yards to the I-77 northbound on-ramp, turn right and get on I-77.

Cleveland

Cleveland, once flat broke, has made a resurgence with a vengeance. This is exemplified in their Convention and Visitors Bureau: marketing Cleveland is their name and they do it well. Their offices are downtown in the Terminal Tower on Public Square.
  If you are eastbound on the Ohio Turnpike (I-80), take exit 151 and follow to I-71 at exit 11. Merge with I-71 northbound and continue through the I-90 interchange (you don't 'exit' here). Keep going (that was the end of I-71 - you are now on I90 eastbound) to exit 171-B. Exit and merge with OH-14. This is Broadway at the Interstate but a few blocks later it becomes Ontario. It is still OH-14 if you can find the signs. When you cross Superior Avenue (US-6), you're getting close. The next street is Frankfort Avenue and 'Public Square' is one block to your left. There are parking garages all over but some of them seem to be reserved for monthly clients. If there is not sign indicating you're not welcome, drive on in. Parking in Cleveland isn't as bad as New York City but they appear to be working hard at catching up. We took a stroll around the area and found our visit very well worth while. If you like to eat good food (vs. what is available in a hurry) there are 8 or 10 very good restaurants in this area. Some are very reasonable (check the prices before you take a table).

Downtown Hotels in Cleveland - We did choke when we found that parking in downtown Cleveland could cost over $20/day (the Hyatt Regency charges $19 for guests! The Radisson Gateway on Huron Rd - the others aren't far behind.
  When we made reservations at the Comfort Inn Downtown on Euclid Ave (right near exit 172 of I-90), theirs was about the best room rate we could find. We hadn't thought to ask about parking. It wasn't free but it was only $6.50 per night with "in and out privileges". The Holiday Inn Express - same room rates and just a few blocks away on Euclid - charges $12. The Hampton Inn - almost next door to the Hyatt Regency and charging about the same room rates - charges $15 if you park yourself; $18 (only a dollar less than the Hyatt) for valet service.
  So there you have it. We stayed at the Comfort Inn, near the Interstate, found everything was within walking distance plus there are four good restaurants within a block.

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Cleveland Botanical Gardens - Like most big city botanical gardens, this one seems to have about everything. But one special attraction is certainly worth taking the effort and time to visit: the giant Glasshouse.
  The newest attraction in the Botanical Gardens, the Glasshouse contains two distinct ecosystems - under glass. One, an emulation of a desert oasis similar to  what you might see on the island of Madagascar. The other, an emulation of a Costa Rican rain forest complete with a river gorge.
  The Botanical Gardens is at 11030 East Boulevard. For more information, phone 216.721.1600 or visit their web site at cbgarden.
  From I-90, take exit 173A and follow US-322 (Chester Ave) eastbound to E. 63rd Street. Turn left, go one block and turn right on Hough Avenue. Follow Hough eastbound past the VA Center to the Botanical Gardens. Hough Ave changes its name to East Boulevard at Liberty Street, just before the VA Center.

Rock and Roll Hall of Fame - where else can you view over 50 rock and roll exhibits, dynamic cinema presentations plus the largest single collection of rock and roll artifacts? Here is is at  One Key Plaza (East 9th Street at Lake Erie). Phone 1-216-781-ROCK.
  Open 10a-5:30p every day except Wednesday when they stay open until 9p. Admission: $18 (kids 9-12, $11; under 8, free).
  If you are already in town, your best route is to follow 9th Street north to Lake Erie.
  If you are on I-90, take exit 174-B and follow OH-2 to the 9th Street exit. The Hall of Fame is on the lake side of the freeway.
  If you are on I-80, take exit 151 - or, if you've passed that exit, take exit 161 - or, if you've passed that or are westbound, take exit 173. Follow I-480, or I-71, or I-77 (respectively) northbound to I-90 and continue on I-90 to exit 174-B. Exit and follow OH-2 to the 9th Street exit. The Hall of Fame is on the lake side of the freeway.